Professional Biography
Dr. Brian Alldredge is Associate Dean for Academic Affairs and Professor of Clinical Pharmacy in the School of Pharmacy. He is also Clinical Professor of Neurology in the School of Medicine, and a member of the UCSF Epilepsy Center. Dr. Alldredge's clinical practice and research interests focus on epilepsy, pharmacogenetics and patient safety. He is an editor of Applied Therapeutics: The Clinical Use of Drugs - a pharmacotherapy text book used widely in health professions education - and he is an Associate Editor for AHRQ Web M&M: Morbidity & Mortality Rounds on the Web (http://www.webmm.ahrq.gov/). He participates on invited review groups for the National Institutes of Neurological Disorders & Stroke, and he serves as a review for journals in pharmacy, neurology and medicine.

Dr. Alldredge's research focuses on the treatment of epilepsy with antiepileptic drugs, pharmacogenetics, status epilepticus, and medication safety in institutions and the community. He is pharmacogenomics core leader for the Epilepsy Phenome / Genome Project - a multicenter consortium of academic medical centers that is exploring the link between genetics and epilepsy phenotypes (including pharmacoresistance). His work is currently supported by grants from the National Institutes of Health and private foundations.

Selected Peer-reviewed Publications

• Lowenstein DH, Alldredge BK. Status epilepticus at an urban public hospital in the 1980s. Neurology 1993;43:483
• Alldredge BK, Lowenstein DH. Status epilepticus related to alcohol abuse. Epilepsia 1993;34:1033-7.
• Lee KC, Finley PR, Alldredge BK. Risk of seizures associated with psychotropic medications: emphasis on new drugs and new findings. Expert Opinion on Drug Safety 2003;2:233-47.
• Alldredge BK. Seizure risk associated with psychotropic drugs: clinical and pharmacokinetic considerations. Neurology 1999;53(Suppl 2):S68-S75. Gottwald MD, Akers LC, Liu PK, Orsulak PJ, Corry MD, Bacchetti P, Fields SM, Lowenstein DH, Alldredge BK. The stability of diazepam and lorazepam as used in the pre-hospital setting. American Journal of Emergency Medicine 1999;17:333-7.
• Alldredge BK, Lowenstein DH. Status epilepticus: new concepts. Current Opinion in Neurology 1999;12:183-90. Aweeka FT, Gottwald MD, Gambertoglio JG, Wright TL, Boyer TD, Pollock AS, Eldon MA, Kugler AR, Alldredge BK. Pharmacokinetics of fosphenytoin in patients with hepatic or renal disease. Epilepsia 1999;40:777-82.
• Alldredge BK, Wall DB, Ferriero DM. Effect of prehospital treatment on the outcome of status epilepticus in children. Pediatr Neurol 1995;12:213-6.
• Alldredge BK, Gelb AM, Isaacs SM, Corry MD, O''Neil N, Gottwald MD, Ulrich SK, Neuhaus JM, Segal MR, Lowenstein DH. A comparison of lorazepam, diazepam, and placebo for the treatment of out-of-hospital status epilepticus. N Engl J Med 2001;345:631-7.
• Alldredge BK, Knutsen AP, Ferriero DM. Anticonvulsant hypersensitivity syndrome: in vitro and clinical observations. Pediatr Neurol 1994;10:169-71.
• Lowenstein DH, Alldredge BK. Status epilepticus. N Engl J Med 1998;338:970-6.
• Lowenstein DH, Alldredge BK, Allen F, Neuhaus J, Corry M, Gottwald M, O''Neil N, Ulrich SK, Isaacs SM, Gelb AM. The prehospital treatment of status epilepticus (PHTSE) study: design and methodology. Controlled Clinical Trials 2001;22:290-309.
• Alldredge BK, Venteicher R, Calderwood TS. Stability of diazepam rectal gel in ambulance-like environments. American Journal of Emergency Medicine 2002;20:88-91.